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Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) |
| Enrichment Score (ES) | -0.8259834 |
| Normalized Enrichment Score (NES) | -1.705422 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.011964904 |
| FWER p-Value | 0.031 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAPK8 | 6459 | 1918 | 0.379 | -0.0819 | No | ||
| 2 | HRAS | 4868 | 2695 | 0.167 | -0.1142 | No | ||
| 3 | SHC1 | 9813 9812 5430 | 3966 | 0.042 | -0.1803 | No | ||
| 4 | AKT1 | 8568 | 4238 | 0.034 | -0.1930 | No | ||
| 5 | SPRED2 | 8539 4332 | 4259 | 0.033 | -0.1922 | No | ||
| 6 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 4399 | 0.030 | -0.1979 | No | ||
| 7 | GRAP2 | 5113 9398 | 6108 | 0.012 | -0.2893 | No | ||
| 8 | KIT | 16823 | 6215 | 0.011 | -0.2943 | No | ||
| 9 | SPRED1 | 4331 | 6238 | 0.011 | -0.2949 | No | ||
| 10 | GRB10 | 4799 | 8037 | 0.005 | -0.3915 | No | ||
| 11 | PTPN11 | 5326 16391 9660 | 9360 | 0.001 | -0.4626 | No | ||
| 12 | SNAI2 | 22848 | 9750 | 0.000 | -0.4835 | No | ||
| 13 | FOXO3 | 19782 3402 | 10282 | -0.001 | -0.5121 | No | ||
| 14 | LYN | 16281 | 10463 | -0.001 | -0.5217 | No | ||
| 15 | PTPRO | 1093 17256 | 10877 | -0.002 | -0.5438 | No | ||
| 16 | MATK | 3425 19930 | 11601 | -0.004 | -0.5825 | No | ||
| 17 | EPO | 8911 | 11715 | -0.005 | -0.5883 | No | ||
| 18 | MITF | 17349 | 11903 | -0.005 | -0.5981 | No | ||
| 19 | DOK1 | 17104 1018 1177 | 12045 | -0.006 | -0.6053 | No | ||
| 20 | PIK3R1 | 3170 | 12501 | -0.008 | -0.6294 | No | ||
| 21 | SOS1 | 5476 | 13043 | -0.010 | -0.6580 | No | ||
| 22 | PIK3CA | 9562 | 13536 | -0.014 | -0.6837 | No | ||
| 23 | EPOR | 19204 | 13803 | -0.017 | -0.6971 | No | ||
| 24 | KITLG | 19889 3342 | 13909 | -0.018 | -0.7017 | No | ||
| 25 | CBL | 19154 | 14583 | -0.031 | -0.7362 | No | ||
| 26 | MAP2K2 | 19933 | 14885 | -0.041 | -0.7501 | No | ||
| 27 | SH2B3 | 5001 16383 | 14979 | -0.045 | -0.7525 | No | ||
| 28 | JAK2 | 23893 9197 3706 | 15078 | -0.050 | -0.7550 | No | ||
| 29 | STAT5A | 20664 | 15080 | -0.050 | -0.7522 | No | ||
| 30 | MAP2K1 | 19082 | 15278 | -0.061 | -0.7594 | No | ||
| 31 | RPS6KB1 | 7815 1207 13040 | 15680 | -0.094 | -0.7757 | No | ||
| 32 | MAP4K1 | 18313 | 16615 | -0.312 | -0.8084 | Yes | ||
| 33 | RAF1 | 17035 | 16923 | -0.414 | -0.8016 | Yes | ||
| 34 | TEC | 16514 | 17142 | -0.506 | -0.7848 | Yes | ||
| 35 | BAD | 24000 | 17315 | -0.582 | -0.7612 | Yes | ||
| 36 | CRKL | 4560 | 17368 | -0.613 | -0.7294 | Yes | ||
| 37 | GRB2 | 20149 | 17370 | -0.613 | -0.6949 | Yes | ||
| 38 | GSK3B | 22761 | 17375 | -0.618 | -0.6602 | Yes | ||
| 39 | MAPK3 | 6458 11170 | 17396 | -0.634 | -0.6255 | Yes | ||
| 40 | SOCS1 | 4522 | 17563 | -0.738 | -0.5928 | Yes | ||
| 41 | VAV1 | 23173 | 17925 | -1.033 | -0.5539 | Yes | ||
| 42 | PTEN | 5305 | 18017 | -1.128 | -0.4952 | Yes | ||
| 43 | GAB1 | 18828 | 18101 | -1.234 | -0.4300 | Yes | ||
| 44 | STAT1 | 3936 5524 | 18114 | -1.257 | -0.3597 | Yes | ||
| 45 | CREBBP | 22682 8783 | 18124 | -1.271 | -0.2885 | Yes | ||
| 46 | PDPK1 | 23097 | 18147 | -1.308 | -0.2159 | Yes | ||
| 47 | STAT3 | 5525 9906 | 18327 | -1.720 | -0.1285 | Yes | ||
| 48 | PTPN6 | 17002 | 18512 | -2.552 | 0.0056 | Yes |
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